CRA Clinical Trial Evaluator

Understand the quality of a clinical trial—not just its conclusions.

Upload a published clinical trial and receive a structured evaluation in minutes. See how well the study was designed, conducted, analysed and interpreted—and what the findings may actually mean in practice.

Evaluate a trial

Try it free: 2 complete evaluations each month. No payment details required.

Automated, guideline-informed appraisal. Reports are not personally reviewed by a CRA scientist unless expressly stated. Confirm important findings against the original paper.

More than a paper summary

Find out whether the evidence deserves to be believed.

The evaluator does not simply repeat the abstract or the authors' conclusions. It checks whether those conclusions are supported by the study methods and results, while keeping study quality separate from whether the treatment produced a meaningful benefit.

Understand the studyA concise summary of the design, participants, treatment, outcomes and main findings.

Assess its trustworthinessClear judgements about trial design, risk of bias, analysis, precision and reporting.

Interpret the effectPlain-English context for effect sizes, statistical findings and whether benefits may be noticeable.

See what mattersKey strengths, limitations, important warning flags and practical considerations.

Put findings into practiceConsideration of possible stand-alone value, adjunctive value and real-world applicability.

Keep a professional reportView the complete evaluation online, ask follow-up questions and download a formatted PDF.

1Upload the published paper

2The trial is systematically evaluated

3View and download your report

Upload the published paper

PDFNo paper selectedChoose a searchable PDF · maximum 20 MB

What the evaluator tells you

Was the trial designed and conducted properly?Checks the study design, treatment groups, participants, outcome measures, missing data and planned reporting.

How strong are the results?Checks whether the analysis is appropriate, how precisely the effect is estimated and whether the conclusion matches the results.

What do the findings mean?Separately considers plausibility, clinical importance, harms and how well the findings apply beyond the people and setting studied.

A comprehensive, guideline-informed clinical trial evaluation system drawing on CONSORT 2025, Cochrane RoB 2, SPIRIT, GRADE principles and ICH clinical-trial guidance. No weighted total is calculated. A serious problem in a key domain can limit the overall conclusion because some parts of a trial are essential for a fair result.

Linked to the paperEach important judgement identifies the page or section of the paper containing the supporting evidence.

Uncertainty is shown clearlyMissing or incomplete information is labelled as unclear. A method is not assumed to be adequate simply because the paper did not describe it.

Critical weaknesses cannot be averaged outA serious problem with an essential feature—such as randomisation, blinding or analysis—can limit confidence in the study even when other aspects are strong.

Introductory pricing

Choose the allowance that suits your work.

Every plan includes the complete evaluation, plain-English interpretation, effect-size assessment, strengths and limitations, a detailed bottom line, PDF report and saved report history.

Free

A$0

No payment required

2 full evaluations each month

Complete reports
Up to five follow-up questions per report
PDF downloads

Create free account

A$19.95/month

Including GST · introductory price

20 full evaluations each month

Everything in Free
Ten times the monthly allowance
Cancel anytime

Pro Plus

A$29.95/month

Including GST · introductory price

30 full evaluations each month

Everything in Pro
For frequent study review
Cancel anytime

Allowances reset monthly and unused evaluations do not roll over. Only successfully completed evaluations count toward the allowance.

My reports

Previous reports

Completed reports are saved privately to your account until you choose to delete them. Uploaded papers are still deleted immediately after evaluation.

Private account history

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Transparency and limitations

About this evaluation

This is an automated, guideline-informed critical appraisal developed by Clinical Research Australia (CRA), a contract research organisation. It applies a structured set of criteria intended to be used consistently, but the algorithm has not been independently validated as a clinical or regulatory decision tool. Unless a report expressly says otherwise, it has not been reviewed or endorsed by a CRA scientist. CRA may have conducted, advised on, or otherwise worked with a study, sponsor, intervention or product being evaluated; users should consider any relevant relationship when interpreting the report. The evaluation is not formal peer review and is not medical, regulatory, legal or investment advice. Important decisions should be checked against the original paper and, where appropriate, reviewed by a suitably qualified independent expert.